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Definition of Heart Disease
The term heart disease (coronary heart disease) is a term that describes many
heart disorders, including high blood pressure, coronary artery disease, and clogging of the arteries.
Any number of diseases related to the heart and blood vessels can come under the
umbrella of heart disease. Grouped together these diseases are the leading cause of death in the Western
The most common types of heart disease occur due to inadequate blood flow to the
NB: Obese people are at increased risk of due to their higher rates of
hypercholesterolemia (high LDL cholesterol), diabetes and hypertension.
Description of a Healthy Heart
Your heart is a living pump. A healthy heart works to keep your blood moving and
oxygenated. A network of blood vessels called coronary arteries supply blood and nutrients to your heart to keep it
functioning in this way.
There are three main coronary arteries – right (RCA), left anterior descending
(LAD) and left circumflex artery (CX).
Each of the coronary arteries branches into smaller arteries that reach all the
areas of your heart muscle.
The heart pumps ‘used’ blood through the lung capillaries where waste gas (carbon
dioxide) is expelled and fresh oxygen is taken up. This fresh oxygenated blood is bright red and is pumped through
the aorta (the main artery of the heart) into the capillaries, where nutrient and oxygen exchange within cells
takes place. It then returns to the heart through veins.
Heart failure, for whatever reason, can be fatal. The heart is one of the hardest
working organs in the body. It contracts and expands around 100,000 times a day, it supplies 96,000 kilometres of
blood vessels and pumps in excess of 10,000 litres of blood around the body each day. This constant action is
stressful and makes this system particularly vulnerable to damage and disease.
Heart disease is any
disorder that affects the heart's ability to function in this normal way.
Some heart diseases can be present at birth (congenital); others develop as we
grow and may be dependant on factors like genetics, diet (nutrition), the environment and toxins; others may be
degenerative (or medical).
Problems can arise in the heart muscle, valves, or surrounding arteries. The most
common form of heart disease is a narrowing or blocking of the coronary arteries (atherosclerosis). Following are
examples of terms used to describe heart disease, followed by brief explanations of the most common
Cardiovascular disease involves the heart and its two networks of blood vessels, the system which circulates the
blood throughout the body and the system which circulates the blood through the lungs.
Coronary artery diseases (CAD) are diseases of the arteries that supply the heart muscle with blood. CAD is one of the
most common forms of heart disease and the leading cause of heart attacks. It generally comes from blood flow
obstructions. The most common cause of such obstructions is a condition called atherosclerosis. Coronary artery
disease can cause other heart problems, such as chest pain angina and heart attack (myocardial
Coronary heart disease is also known as ischemic heart disease and is similar to coronary artery disease but a
broader term that refers to both diseases of the arteries and their resulting complications, (chest pain, heart
attacks and scar tissue).
Cardiomyopathy is a
condition that includes all diseases of the heart muscle. Types of cardiomyopathy include ischemic, which is caused
by loss of heart muscle from a heart attack; dilated, which means the heart is enlarged; hypertrophic, which means
the heart muscle is thickened; and idiopathic or dilated idopathic, which means an enlarged heart without a known
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To the left is a normal, healthy heart - It has a complex grouping of outer
muscles that work together to pump blood through the body.
To the right is a weak, diseased heart - This is a heart with muscle disease. It
looks larger than a healthy heart. A heart like this cannot pump blood properly.
Valvular heart disease is a disease of the heart valves, narrowing, leaking or improper closure.
Pericardial disease is
a disease of the sac that encases the heart (pericardium). Fluid accumulation (pericardial effusion) and stiffness
(constrictive pericarditis). These can occur alone or together.
Congenital heart diseases are forms of heart disease that develop before birth and affect the formation of the heart
muscle or its chambers or valves. Some congenital heart defects may be apparent from the time of birth, while
others may not be detected until later in life.
Heart failure is not a
condition where the heart stops. It is a condition which describes the heart not being able to pump blood
adequately to the body's organs and tissues. Vital organs don't get enough blood, and therefore oxygen, causing
signs like shortness of breath, fluid retention and fatigue.
Blood vessels diseases
There are four types of blood vessels. They are:
- Arteries that carry blood away from your heart and out to your body,
delivering oxygen and nutrients.
- Veins that carry deoxygenated blood back to your heart.
- Capillaries that connect arteries and
- Lymphatics that carry this fluid back to the central circulatory
Types of blood vessel disorders include:
Arteriosclerosis and atherosclerosis
Arteriosclerosis is a condition in which the walls of your arteries become thick and stiff. Restricting
blood flow to organs and tissues.
Atherosclerosis is the
most common form of arteriosclerosis, referring to hardening of the arteries caused by accumulation of fatty
deposits (plaques), often calcified, develop on the inside of the arterial walls and eventually cause blockages
which lead to cardiovascular disease.
When the arteries of the heart narrow, you may experience chest pain or a heart
Atherosclerosis is the
result of the body's attempt to ‘repair’ injuries to the inside of the arterial walls. These injuries come about
because of weaknesses in the walls and their exposed stress from the constant pumping action of the heart. Stress
is increased by high blood pressure (hypertension) and emotional trauma.
The prevention of heart disease, heart attacks and strokes is synonymous with the
prevention of atherosclerosis.
High blood pressure
Hypertension is the excessive force of blood pumping through your blood vessels due
to restrictions. It affects 1 in every 4 people.
It is important to remember that hypertension is not a condition. It is a symptom
of an underlying problem...ie. narrowing arteries. In societies that do not have high cardiovascular disease rates,
high-fat diets and obesity, or stressful, fast modern lives, hypertension does not occur. It is a common symptom of
underlying stress or body malfunction. If this cause is pinpointed and treated, the hypertension will naturally
subside to normal levels.
Common underlying causes that bring about high blood pressure including lifestyle
issues such as excess alcohol, caffeine, high salt intake, hormone therapies, stress, anxiety and lack of exercise,
as well as conditions like diabetes, arteriosclerosis, high cholesterol, and many of the cardiac diseases listed
Although potentially life-threatening, because hypertension is a symptom of a
condition it is very much preventable and curable. If left untreated, the symptom will of course worsen, putting
undue pressure on the heart muscle and depleting blood vessel strength. After a period of time this will lead to
serious cardiac disease such as stroke and heart failure.
A stroke is a sudden loss of brain function. It occurs when blood flowing to the
brain is interrupted (ischemia) or when blood vessels in the brain rupture (haemorrhage). Stroke can cause a number
of neurological complications.
An aneurysm is a
bulge or weakness in the wall of an artery or vein. Aneurysms usually enlarge over time, and because of this they
have the potential to rupture and cause life-threatening bleeding. Aneurysms can occur in arteries in any location
in your body.
Peripheral arterial disease and claudication
Claudication is when you experience pain in your arms or legs during exercise, a
symptom of peripheral arterial disease. It is a disorder in which the arteries supplying blood to your limbs become
clogged or partially blocked. Pain or cramping is commonly the first sign.
This refers to
an inflammation of the blood vessels. Vasculitis can affect the arteries, veins or capillaries. The inflammation
may impair general blood flow.
is a condition in which blood flows the wrong way through your veins. Veins have tiny valves that are designed to
promote blood flow in a forward direction, i.e. back to the heart. However, if you happen to be suffering from
infection, inflammation, abnormal blood clotting, or even high-back pressure in pregnancy, the valves may become
damaged, allowing blood to flow backward and ‘pool’ in your legs.
Venous imcompetence can lead to the development of such complications as prominent
and painful varicose veins, skin changes, ulcers and swelling in your legs.
When venous incompetence occurs in your arms, you may experience pain and swelling
in your arms and prominent veins may appear.
the formation of a blood clot (thrombus) in a vein that may damage the vein or it’s valves. Clots that break off
and travel in the bloodstream can lodge in the lungs, (pulmonary embolism). This type of clot may cause a stroke.
Deep vein thrombosis is where a similar clot develops deep within a muscle.
This is a condition in which your veins become twisted and enlarged. The veins are
usually located on the backs of your calves or on the inside of your legs. When valves in your veins don't function
properly, blood can accumulate in your legs, causing the veins to bulge and twist.
This is an obstruction of the lymphatic vessels that causes an excessive build-up of
fluid, resulting in swelling and pain.
Heart Disease Statistics
"Heart and blood vessel diseases kill more than 16 million people worldwide
and account for 30% of total deaths each year.” ------(World Health Organization)
Cardiovascular diseases are the number one killer of both women and
- More than 1.5 million heart attacks occur every year in the
- 50 million Americans have high blood pressure.
- Every 20 seconds an American suffers a coronary event. Every 34
seconds someone dies from heart disease.
- CVD kills 4 million Europeans each year. It's the No 1 cause of
- 1 British adult dies from heart disease every 3 minutes.
- Strokes claim over 70,000 UK lives each
Cardiovascular disease is very much a disease of Western civilization.
Causes of Cardiovascular Disease
Decades of research show that poor lifestyle choices, beginning in childhood, are
the main causes of cardiovascular / heart disease. Ongoing factors, such as poor diet, nutritional deficiency,
nutritional inadequacy - which is a separate issue to deficiency, as it is referring to the inability of the
digestive system to function properly, and hence lack of nutrients absorbed and assimilated, not the actual oral
ingestion of nutrients - plus lack of exercise, poor fluid intake and increased toxicity and stresses form a recipe
for circulatory disaster.
All of the above are major risk factors. More specifically, high blood pressure -
hypertension (itself a result of any/all of the above), tobacco use, increased intake of saturated fats, lack of
essential antioxidants (excessive exposure to free radicals via pesticides, chlorinated water, air pollutants and
other toxic chemicals, for example, is a strong risk factor for cardiovascular disease), elevated blood
cholesterol, convenience lifestyle (i.e. reduced exercise) and genetic predisposition.
All these and more lead to increased stress factors, obesity and diabetes... in
turn leading to heart attacks, strokes, artherosclerosis, and more
NB: Stress not only raises the blood pressure and constricts the
arteries, it also generates large quantities of adrenalin which the body converts to adrenochrome - a
potent free radical.
The more ‘risk factors’ you have, the more likely you are to develop heart
disease. All of these factors, bar genetic factors, can be changed and treated, even genetic risks can be modified
with proper treatment.
Blood pressure can vary with activity and age, but a healthy adult who is resting generally
has a systolic pressure reading between 120 and 130 and a diastolic pressure reading between 80 and 90
Free radical activity plays a major role in the development and progression of atherosclerosis in particular, through
oxidized lipoproteins and through direct attacks on the DNA of the arterial wall cells.
As the body attempts to repair damage to arterial walls, smooth-muscle cells (at
the centre of the repair) themselves accumulate cholesterol and oxidized lipoproteins, and may begin to undergo
calcification. As these deposits grow the inside opening of the artery begins to narrow, eventually create a
blockage. If the blockage is in the coronary arteries angina pectoris may develop, or a heart attack may occur. If
it is in the brain a stroke may occur, and if the blockage is in the legs intermittent claudication (pain or
fatigue in arms and legs due to poor supply of oxygen to the muscles) may be experienced.
Iron has more recently
been implicated in heart disease development. Researchers at Harvard University have concluded that it is not the
overall iron intake that increases heart attack risks, but rather the specific intake of iron from red meats –
potentially increasing your disease risk by up to 38%!
Cholesterol levels, and more
specifically high LDL (low density lipoprotein) levels, are strong risk factors for cardiovascular disease,
especially for men. Too much LDL cholesterol in the blood causes plaque to form on artery walls (the beginning of
atherosclerosis). When this occurs arteries that supply blood to the heart get blocked (see description above) and
you become at high risk of a heart attack.
Cholesterol is a soft, buttery substance. If the only build-up on the inside of the
arteries were cholesterol, it would not get hard and the flow of blood would wash away the stuff. But, when that
cholesterol gets mixed up with calcium the combination of the two becomes hard. That is why the honest term, used
before the drug companies started fiddling with the facts, was 'hardening of the arteries'.
Homocysteine is an amino acid in the blood, high levels of which can significantly
increase the risk of cardiovascular disease.
Mercury toxicity and Helicobacter pylori bacterium infection are potent initiators
of coronary heart disease.
It is not often well understood that heart problems are actually a consequence
(and symptom) of diabetes, and are the leading cause of death among diabetes sufferers, especially in adult-onset,
or Type II diabetes. The American Heart Association estimates that 65% of patients with diabetes die of some form
of cardiovascular disease.
Obesity…Being overweight is,
alongside diabetes, the leading cause of increased cholesterol levels, high blood pressure and coronary artery
disease. Obesity increases your chances of developing all these risk factors in fact, as well as putting
unnecessary strain on many other organs.
NB: Just from these
short summaries you may be beginning to notice how all these conditions clearly interlink with one
Smoking, as well as
increasing your risk of lung cancer, increases risks of heart disease and peripheral vascular disease. More than
400,000 deaths in the US alone occur each year because of the straining effects this habit has on the heart and
Research has shown that smoking increases the heart rate, tightens major arteries
and can create irregularities in the timing of heartbeats, all of which make your heart work harder.
Although nicotine is the main active agent in cigarette smoke, other chemicals and
compounds like tar and carbon monoxide are harmful to your heart too and lead to plaque build-up and injury to the
protein (CRP) is a substance found in blood that is a marker for inflammation in the body. High levels of this
protein are associated with an increased risk of heart disease and low levels with a low risk.
Studies suggest that CRP levels may even be a more important indicator of heart
disease risk than high LDL cholesterol!
"In an eight-year study involving 27,939 women
led by Paul Ridker, MD, director of the Center for Cardiovascular Disease Prevention at Brigham and Women's
Hospital in Boston, more than half of the women who eventually developed heart disease had high CRP levels
even though their LDL levels were not considered high. "
The New England Journal of Medicine
"A Cleveland Clinic study found ultrasound
evidence that clogged coronary arteries had not gotten worse among 502 patients who were most successful at
lowering their CRP levels. "
The New England Journal of
"A recent study at showed that as fitness levels
go down, CRP levels go up. "
To help lower CRP levels it is recommended to concentrate on an anti-inflammatory
diet, plus Omega 3 DHA fish oil supplements and anti-inflammatory and antioxidant supplement ingredients which
include methylating agents to reduce homocyteine.
Finally, other indirect factors include…
Physical Inactivity -
People who are inactive have a greater risk of disease leading to a heart attack. Exercise burns calories, helps to
control cholesterol and diabetes, and may help to lower blood pressure. Exercise also strengthens the heart muscle
itself and makes the arteries more flexible. Even moderate exercise is helpful if done regularly.
Genetics - Risk factors
(high blood pressure, diabetes and obesity) may be passed from one generation to another.
Stress - We all deal
with stress differently. How much and in what way stress affects us can vary from person to person. During times of
stress the nervous system releases extra hormones (e.g. adrenaline). These hormones can raise blood pressure and
injure the lining of the arteries. When the arteries heal the walls may harden or thicken, making is easier for
plaque to build up.
Stress also increases the amount of blood clotting factors that circulate in your
blood. Clots may block an artery already narrowed by plaque, resulting in a heart attack.
Nutritional deficiency and
It is never too late to begin improving heart
health. By eliminating risk factors, properly managing your health, and optimising your systems - first
your digestive system, then others - you can greatly reduce your risk of heart disease, and even begin to
heal disease that is already present.
Most people become vulnerable to these diseases
because of a weakened immune system and systemic and organ-related weaknesses as a result of inadequate
nutrition. This more often than not starts in early life, but continues to reduce health throughout life.
Nutritional deficiencies, chemical and environmental toxicities are the major reason for the accentuation
of most, if not all of the above risk factors.
Diagnosis of Cardiovascular Disease
Sadly, in most cases the first indication of cardiovascular disease is an actual
acute heart event. This is because many of the underlying symptoms are either mistakenly considered a consequence
of some other condition or disease, or they are simply misdiagnosed.
On most occasions symptoms are not noticed by the patient until such time that
they cause a major condition….often being put down to another unrelated condition, being ‘run down’, or being under
Angina pectoris (chest
pain) and stroke (cerebral infarction) are the most common physical symptoms that are first
If prior symptoms are realised, techniques and equipment can be used to confirm a
tests particularly indicative for people with high risk factors (smoking, diabetes, obesity and hypertension). They
can even show if a patient has already suffered a mild heart attack without noticing it.
Radioisotopes help to
spot blood flow problems.
An Echocardiography is useful to evaluate the
Position emission tomography (PET scanning), CT scanning and magnetic resonance spectroscopy are also commonly
Coronary arteriography is an invasive technique used to determine the extent and
location of blockages in coronary arteries. It is only used prior to heart surgery such as angioplasty or bypass
As in all cases of potentially chronic illness, a thorough history - medical and
genetic - should be taken, along with lifestyle, nutritional and dietary implications, and any other factors to
help determine risk and current health statistics.
Signs & Symptoms
As mentioned above, often symptoms are not noticeable until an actual stage of
disease has already manifested. Some symptoms associated with coronary artery disease may be more pronounced
however. Such signs include:
Angina (chest pain) - This is the most common symptom, resulting from the heart intermittently not getting enough
blood or oxygen. The intensity of the pain may vary from person to person.
Typical chest pain is
felt under the sternum and is characterised by a heavy feeling, or a feeling of the chest being squeezed. Pain may
also radiate to the shoulders, neck, or arms. It is often precipitated by exertion or emotional stress and is
relieved by rest.
Women may also have a tendency to experience some areas of swelling - the ankles
and legs for example – plus stomach upset, dizziness, rapid heartbeats, shortness of breath and chronic
Shortness of breath –
This can be a symptom of congestive heart failure (among many other things). The heart may be weak due to lack of
blood and oxygen, resulting in shortness of breath accompanied by swollen feet and ankles too due to the reduced
When A Heart Attack is experienced you may experience intense chest pain that can
be acute or last for a more extended period of time. There may be a sensation of pressure, burning, tightness,
heaviness, or squeezing behind the breastbone. Pain in the left arm or jaw and of course laboured breathing also
may occur. Alternatively pain may be more diffuse, spreading to the shoulders, neck, arms, abdomen and even back.
Pain my come and go, feeling like a heaviness or burning sensation in the chest rather than intense
Some victims of coronary heart disease experience none of these symptoms, while
others experience them at varying levels. Initial emergency treatment is often recommended, such as the chewing of
a regular strength adult Aspirin to inhibit blood clotting in the affecting coronary artery.
Stroke symptoms include a number of warning signs:
- Changes in vision
- Leg, arm, or face weakness
- A sudden, severe headache
- Changes in speech and hearing
- Unsteadiness or unexplained dizziness
- Nausea, vomiting, or drowsiness
Symptoms may be especially noticeable on one particular side of the
Heart Failure symptoms may include:
- Shortness of breath
- Persistent coughing
- Swelling of the feet, ankles, legs, or abdomen.
Symptoms may continue for years unnoticed as the heart weakens.
Treatment of Heart Disease
As is the case with most degenerative diseases there are two avenues of treatment
- conventional (allopathic) and alternative (natural) treatment.
Conventional medicine employs surgery and drugs to treat the symptoms of
On the other hand, alternative methods concentrate on the whole body and
underlying problem to bolster the body's natural healing powers and focus on removing the actual cause of the
disease rather just treating the symptoms.
Conventional medicine helps to diagnose and treat acute, life-threatening events,
but natural ‘holistic’ methods are more gentle, have far fewer side effects and are capable of actually reversing
heart disease and regaining full health as well as working to protect and prevent disease occurring in the first
Lifestyle changes are of course the first line of prevention and treatment of
Conventional medicine recommends medical interventions ranging from drugs to
surgery. For example, a bypass operation may be performed to reduce a person's risk of a heart attack, or to try to
help stop any further heart attacks from taking place. When this operation is performed a blood vessel from another
body area is used to ‘re-route’ blood around the blocked artery.
Many prescription medications are used every day to help prevent or control
coronary heart disease (CHD). However, if medications are needed lifestyle changes still must be undertaken for
results to take effect.
Common Drugs used to
treat CHD include:
Aspirin helps to lower
the risk of a heart attack for those who have already had one. It also helps to keep arteries open in those who
have had a previous heart bypass or other procedure.
However, because of its side effects aspirin is not approved by the Food and Drug
Administration in the US for preventing heart attacks in healthy individuals with careful assessment.
Some of the most common aspirin side effects are stomach pain, heartburn, nausea
and vomiting. (An aspirin overdose or higher dosage than recommended can cause very serious health
Long-term use of Aspirin has shown to cause gastrointestinal tract complications,
including micro-bleeding and ulcers. There is also a risk of haemorrhagic stroke.
converting enzyme) inhibitors stop the production of a chemical that makes blood vessels narrow and is used to help
control high blood pressure and help heal damaged heart muscle. It may be prescribed after a heart attack to help
the heart pump more efficiently. It is also used for heart failure cases.
Side effects may include a dry cough, headache and dizziness. ACE inhibitors may
also cause elevated amounts of potassium. More rare side effects can include skin rashes, kidney problems, and
swelling of the face, lips and throat.
Example drugs: Benazepril (Lotensin), Captopril (Capoten), Enalapril (Vasotec),
Fosinopril (Monopril), Lisinopril (Prinivil, Zestril), Moexipril (Univasc), Perindopril (Aceon), Quinapril
(Accupril), Ramipril (Altace), Trandolapril (Mavik).
Angiotensin II Receptor Blockers
Angiotensin II constricts blood vessels and causes the kidneys to retain more fluid. The main
function is to increase blood pressure. Angiotensin II receptor blockers (ARBs) inhibit the effects of angiotensin
II by blocking the receptor, thereby reducing constriction and helping to reduce blood pressure.
ARBs also help to minimize over-exertion of the heart muscle and help prevent
progression to heart failure. ARBs are mainly used when ACE inhibitors are not tolerated by the
Side effects may include headache, lightheadedness, nasal congestion, back and leg
pain, diarrhea, rash, indigestion and insomnia. More rare side effects may include kidney failure, liver failure,
allergic reaction, reduced white blood cell count and swelling of tissues (angioedema).
Because ARBs can cause birth defects they are not recommended if pregnant or
planning to become pregnant.
Example drugs: Candesartan (Atacand), Eprosartan (Teveten), Irbesartan (Avapro),
Losartan (Cozaar), Olmesartan (Benicar), Telmisartan (Micardis), Valsartan (Diovan).
Do angiotensin II receptor
blockers increase MI risk, or do they not?
A pair of articles in ‘Circulation’ magazine/journal discusses the
controversy over whether or not angiotensin-II-receptor blockers (ARB) result in a paradoxical increase in
risk of myocardial infarction (MI), despite reducing blood pressure. (Also raised, in a BMJ editorial in
Suggesting that these drugs do increase the risk
of MI argue firstly that in general, clinical trials with ARB have not shown the reduction in MI risk that
could have been expected given the drop in blood pressure that they achieve. They discuss the major trials
involving ARB, and also the various (and discordant) meta-analyses that have been carried out….
Blood clots can block blood flow to the heart or brain, causing a heart attack or
stroke. Antiplatelet medications work by preventing platelets from sticking together to form blood clots to reduce
the risk of a heart attack or stroke occurring, specifically in people who have already had a heart attack or
stroke, or who have poor circulation that causes pain.
Possible side effects include allergic reaction (sneezing, respiratory congestion,
swelling of throat, restricted breathing, itching or skin rashes), nausea, indigestion or stomach pain, unusual
bleeding or bruising, ringing in ears (tinnitus), bloody urine, convulsions or seizures (rare).
Example drugs: Clopidogrel (Plavix), Ticlopidine (Ticlid).
Beta blockers slow the
heart and make it beat with less force, so blood pressure drops and the heart works less hard. It is used for high
blood pressure, chest pain and to prevent a repeat heart attack.
The most common side effects are cold hands and feet, tiredness and sleep
disturbance (nightmares). Less common side effects include, impotence, dizziness, wheezing, digestive tract
problems, skin rashes and dry eyes.
Example drugs: Acebutolol (Sectral), Atenolol (Tenormin), Atenolol Injection
(Tenormin Injection), Bisoprolol (Zebeta), Carteolol (Cartrol), Metoprolol ER (Toprol XL), Metoprolol Oral
(Lopressor), Nadolol (Corgard), Pindolol (Visken), Propranolol (Inderal), Propranolol ER (Betachron ER, Inderal LA,
Innopran XL), Timolol Oral (Blocadren).
Guidelines issued by the NHS
drugs watchdog have given new advice on which medicines should be used to treat high blood pressure.
They recommend that beta-blockers should no longer be routinely used, expect in special
There is also increasing evidence that the most
frequently used beta-blockers can carry a higher risk.
Nitrates (including nitroglycerine) – relax blood vessels and stop chest pain.
Side effects include a feeling of pulsating fullness in the head (most common side
effect) or a headache, a drop in blood pressure, which can cause dizziness or a burning sensation under the
Example drugs: Isosorbide Dinitrate, Sublingual and Chewable (Isordil,
Sorbitrate), Isosorbide Mononitrate (Imdur, Ismo, Isotrate ER, Monoket), Nitroglycerin ER (Nitroglyn),
Nitroglycerin Ointment (Nitro-Bid Ointment, Nitrol), Nitroglycerin Skin Patches (Deponit, Minitran, Nitro-Dur,
Nitrodisc, Transderm-Nitro), Nitroglycerin Spray (Nitrolingual).
Calcium channel blockers – relax blood vessels and are used for high blood pressure and chest pain.
Side effects can include drowsiness, increased appetite, weight gain, breathing
difficulties (shortness of breath, coughing, or wheezing), irregular or slow heartbeat, allergic reactions (skin
rash or hair loss), constipation, tenderness or bleeding of the gums, swelling of feet, ankles and legs, and
Example drugs: Amlodipine (Norvasc), Bepridil (Vascor), Diltiazem ER (Cardizem CD,
Cardizem LA, Cardizem SR, Cartia XT, Dilacor XR, Diltia XT, Taztia XT, Tiamate, Tiazac), Felodipine (Plendil),
Isradipine (DynaCirc), Nicardipine (Cardene), Nicardipine SR (Cardene SR), Nifedipine ER (Adalat CC, Afeditab CR,
Nifediac CC, Procardia XL), Nisoldipine (Sular), Verapamil (Calan, Isoptin), Verapamil Extended-release (Calan SR,
Covera-HS, Isoptin SR, Verelan, Verelan PM).
Oral Anticoagulants -
these are like antiplatelets, but work to dissolve blood clots that have already formed. By dissolving the blood
clots anticoagulants can lower the risk for heart attack and stroke.
Side effects may include bleeding from gums, nosebleeds, pinpoint skin spots,
heavier bleeding, cough or hoarseness, fever or chills, lower back or side pain, painful or difficult urination,
skin rash, hives and itching, blisters, blue or purple toes, ulcers, or white spots in mouth or throat, swelling of
face, feet, or lower legs and yellow eyes or skin.
Example drugs: Warfarin (Coumadin, Jantoven), Hepalin injection.
Salicylates - reduce
pain and swelling by blocking the body's production of chemicals that cause inflammation.
Salicylates (see Aspirin above) are also used to help prevent platelets from
sticking together to form blood clots. These medications can reduce the risk of heart attack or stroke,
specifically in people with poor circulation.
Side effects can include bloody stools, bloody or cloudy urine, fever, chills,
pain in lower back, skin rash, hives, itching, ulcers, white spots on lips or in mouth, sore throat, stuffy nose,
swelling of face or extremities, unusual bleeding or bruising, tiredness or weakness, vomiting, weight gain, yellow
eyes or skin, heartburn or indigestion nausea, vomiting, or stomach pain, drowsiness, trouble sleeping, nervousness
Example drugs: Aspirin Gum.
Diuretics (‘water pills’) - decrease fluid in the body and are used for high blood pressure.
Side effects may include black stools, blood in urine, cough or hoarseness, fever
or chills, joint pain, lower back or side pain, pinpoint red skin spots, skin rash or hives, stomach pain, nausea
and vomiting and yellow eyes or skin.
Diuretics can also be associated with potassium and/or sodium loss…
Signs of potassium loss can include dryness of mouth, increased thirst, irregular
heartbeat, mood changes, muscle cramps or pain, nausea or vomiting, unusual tiredness or weakness and a weak
Signs of sodium loss can include confusion, convulsions, decreased mental
activity, irritability, muscle cramps and unusual tiredness or weakness.
Blood cholesterol-lowering agents - decrease LDL cholesterol levels in the blood.
Side effects include soreness, aches, pain, weakness, fatigue, difficulty walking or
getting out of bed. Also many reports exist on the use of Statin drugs and muscle or nerve damage.
of Statins Carry Dangers, Swedish Report Says (press release)
July 14, 2006
The American National Cholesterol Education
Program said last year that people at high risk of heart disease should be treated more aggressively.
Aggressively lowering cholesterol means that LDL cholesterol should be lowered to less than 1.81 millimoles
per liter of blood (mmol/l) in high-risk individuals. Current guidelines generally recommend 2.56
According to Uffe Ravnskov, an independent
researcher from Lund, Sweden, achieving this new goal would mean that most of the western world's adult
population would be on statins, and doses would have to be more than eight times higher than currently
Doses this high would increase both the number
and seriousness of side effects, Ravnskov's team contended. Side effects could include heart failure,
myalgia and rhabdomyolysis (which destroys muscle tissue), neurological problems and cancers.
In addition, the researchers claimed that
clinical trials suggest that higher doses of statins do not lower overall mortality, and side effects are
Thrombolytic agents -
also called ‘clot busting drugs’, given during a heart attack to break up a blood clot in a coronary artery in
order to restore blood flow.
Side effects may include bleeding from cuts, gums, or wounds, fever, low blood
pressure, agitation, bloating, blue or purple toes, blurred vision, bruising, changes in facial skin, chest
discomfort, chills, confusion, decreased urine output, depression, dizziness, irregular breathing, skin flushing,
headache, indigestion, lethargy, muscle cramps or spasms, twitching, nervousness, numbness, pounding in the ears,
rapid weight gain, shortness of breath, sweating, swelling of eyes, face, lips, or tongue, unusual tiredness or
weakness, vomiting, weakness in arms or legs, and yellow eyes or skin.
Example drugs: Alteplase (Activase), Anistreplase (Eminase), Reteplase
Streptokinase (Streptase), Tenecteplase (TNKase), Urokinase (Abbokinase).
Glycoprotein IIb/IIIa Inhibitors - these are antiplatelet medications that work by preventing the blood from clotting during
chest pain or a heart attack, or when undergoing surgical or procedural treatment.
Side effects may include bleeding, stomach, intestines, or other internal organs,
increased bruising, stomach irritation and allergic reaction.
Example drugs: Abciximab Injection (ReoPro), Eptifibatide (Integrilin), Tirofiban
Natural Treatments for Heart Disease
RECOMMENDED SPECIALTY SUPPLEMENT
Whereas conventional drugs aim to suppress and stem symptoms, the natural approach
aims at containing and even reversing the underlying causes of cardiovascular disease, such as the beginning of
atherosclerosis. Nutritional supplements and dietary interventions are generally based on the principles that aim
at preventative measures too.
While there are many heart healthy tips we can provide, diet and lifestyle changes
and correct nutritional supplementation are categorically the most important tools in the natural treatment of
For example…atherosclerosis can be prevented by developing strong artery walls, by
controlling the factors that cause injuries to them and by minimizing the level of fats, lipoproteins, cholesterol
and homocysteine build up. All of these areas can be potentially controlled and reversed by nutritional and
supplementation methods, but the right nutrients need to be used in the right amounts to maintain a healthy
Some of the most effective nutrients, such as the powerful natural enzyme called
Nattokinase, have to be taken in an enteric coated
tablet because otherwise they can be destroyed by stomach acid.
Nattokinase is clinically proven to help clean arteries and is a powerful anti-clotting agent.